We observed a fascinating case involving a male in his 40s who experienced persistent inflammatory back pain for three months. Despite having a negative test for HLA-B27, a marker often associated with axial spondyloarthritis, clinical assessments suggested possible underlying issues.
The clinical investigation led to an MRI, which confirmed bilateral symmetrical sacroiliitis. Interestingly, further tests showed he had very low vitamin D levels along with elevated parathyroid hormone—indicating a possible deficiency impacting his condition.
After starting treatment with vitamin D alongside nonsteroidal anti-inflammatory drugs (NSAIDs), he experienced notable relief from his symptoms. His condition improved significantly, and follow-up tests indicated that his vitamin D levels had normalized.
This case demonstrates the potential benefits of vitamin D in managing back pain, especially when classical markers are inconclusive. It highlights how a thorough diagnosis can reveal interconnected health issues and improve treatment outcomes.
Read More
9.5
Magnesium reduces postoperative back pain
Effect of perioperative intravenous magnesium sulfate on postoperative pain after iliac venous stenting.
We explored the effectiveness of magnesium sulfate (MS) in relieving low back pain (LBP) for patients who underwent iliac venous stenting. This study involved 97 patients, divided into two groups: one received MS infusion during their surgery, while the other did not.
Patients who received MS experienced significantly lower pain levels at all follow-up intervals. We found that, at 24 hours after surgery, those in the magnesium group consumed much less tramadol—a common pain medication—compared to the control group. Additionally, the need for extra pain relief was lower among those who received magnesium.
Importantly, the side effects like nausea and vomiting were similar in both groups, indicating that magnesium can be a safe option for pain management after this type of surgery. Overall, the findings suggest that magnesium sulfate not only alleviates pain but also reduces reliance on opioids, making it a valuable treatment for postoperative care.
Read More
8
Vitamin D alleviates back pain
The effectiveness of vitamin D3 supplementation in improving functional outcome of non-surgically treated symptomatic lumbar spinal stenosis: Randomized controlled clinical trial - Pilot study.
We conducted a randomized controlled trial to investigate how vitamin D supplementation might alleviate lower back pain in patients suffering from lumbar spinal stenosis. This study involved patients with severely low vitamin D levels, specifically under 10 ng/mL. Participants were divided into two groups: one received vitamin D supplements, while the other did not.
Over a period of several weeks, we measured pain levels and functional recovery using simple questionnaires and health surveys. Notably, we observed that those who received vitamin D injections reported significant improvements in their back pain and overall quality of life compared to those who didn’t.
Our findings suggest that addressing vitamin D deficiency might play a crucial role in managing back pain for individuals with spinal stenosis who are not candidates for surgical intervention. The results demonstrate a promising correlation between high-dose vitamin D supplementation and enhanced functional outcomes in these patients.
Read More
Most Useful Reviews
9
Improved back pain
20 people found this helpful
I usually don’t write reviews, but I have to share. After two months of taking these vitamins, my back pain has ceased, and I wake up feeling refreshed. My cycle has normalised, and I’ve noticed significant hair growth. I highly recommend this for health!
Read More
10
Eliminated back pain
14 people found this helpful
I often suffered from back pain during my monthly cycle, but this raw calcium has completely alleviated it! I had previously experienced calcium deficiencies and chest pain from other supplements. Now, I hardly notice it’s that time of the month due to the absence of back pain.
Read More
9
Pain-free movement
7 people found this helpful
The best! After taking this for a couple of weeks, my osteoarthritis and osteoporosis pain disappeared. I was dancing again! When I ran out and couldn’t afford more, the pain returned until I found it cheaper on Amazon. This product works well when taken as recommended.
We observed a fascinating case involving a male in his 40s who experienced persistent inflammatory back pain for three months. Despite having a negative test for HLA-B27, a marker often associated with axial spondyloarthritis, clinical assessments suggested possible underlying issues.
The clinical investigation led to an MRI, which confirmed bilateral symmetrical sacroiliitis. Interestingly, further tests showed he had very low vitamin D levels along with elevated parathyroid hormone—indicating a possible deficiency impacting his condition.
After starting treatment with vitamin D alongside nonsteroidal anti-inflammatory drugs (NSAIDs), he experienced notable relief from his symptoms. His condition improved significantly, and follow-up tests indicated that his vitamin D levels had normalized.
This case demonstrates the potential benefits of vitamin D in managing back pain, especially when classical markers are inconclusive. It highlights how a thorough diagnosis can reveal interconnected health issues and improve treatment outcomes.
Read More
9.5
Magnesium reduces postoperative back pain
Effect of perioperative intravenous magnesium sulfate on postoperative pain after iliac venous stenting.
We explored the effectiveness of magnesium sulfate (MS) in relieving low back pain (LBP) for patients who underwent iliac venous stenting. This study involved 97 patients, divided into two groups: one received MS infusion during their surgery, while the other did not.
Patients who received MS experienced significantly lower pain levels at all follow-up intervals. We found that, at 24 hours after surgery, those in the magnesium group consumed much less tramadol—a common pain medication—compared to the control group. Additionally, the need for extra pain relief was lower among those who received magnesium.
Importantly, the side effects like nausea and vomiting were similar in both groups, indicating that magnesium can be a safe option for pain management after this type of surgery. Overall, the findings suggest that magnesium sulfate not only alleviates pain but also reduces reliance on opioids, making it a valuable treatment for postoperative care.
Read More
9
Calcium aids in back pain relief
Regular sling core stabilization training improves bone density based on calcium and vitamin D supplementation.
We explored the impact of calcium and vitamin D supplementation combined with sling core stabilization training on back pain in a 70-year-old female patient suffering from osteoporosis. The patient engaged in this form of exercise three times a week, focusing on strengthening the deep muscles of her spine.
After a year of dedicated training, not only did her back pain significantly improve, but a follow-up examination also indicated an increase in her bone mineral density. This suggests that the combined approach of exercise and supplementation might promote better bone health and potentially reduce pain.
However, it’s important to note that while we saw positive changes in this case, the specific contributions of calcium alone cannot be clearly identified due to the concurrent treatments involved. Therefore, we recognize that further studies are needed to isolate calcium's effects to conclusively determine its role in managing back pain effectively.
Read More
9
Vitamin D aids back pain relief
Adult-onset hypophosphatemic osteomalacia as a cause of widespread musculoskeletal pain: A retrospective case series of single center experience.
We conducted a retrospective review to uncover how vitamin D treatment impacts back pain in individuals diagnosed with adult-onset hypophosphatemic osteomalacia. In our exploration, we found that eight patients, primarily experiencing widespread musculoskeletal pain, were assessed over a span from January 2011 to December 2019.
Each patient presented with low phosphorus levels, elevated alkaline phosphatase, and indicative imaging results. Notably, back pain was reported as the most common complaint, along with muscle weakness in over half of the cases. Our findings highlighted the effectiveness of vitamin D in tandem with phosphorus supplementation, as all patients reported significant improvements in pain, muscle strength, and gait after receiving treatment.
Importantly, we noted that the specific diagnosis of each patient varied. In six cases, treatment was prompted by adefovir-induced Fanconi syndrome, while the remaining two patients had tumor-induced osteomalacia and light-chain nephropathy. This variation indicates the diverse etiologies of hypophosphatemic osteomalacia, further emphasizing the importance of targeted treatment based on individual needs.
In conclusion, our study suggests that vitamin D, especially when combined with phosphorus, plays a crucial role in alleviating back pain associated with this condition. By enhancing the understanding of the relationship between vitamin D treatment and back pain, we aim to shed light on effective management strategies for those suffering from similar symptoms.
Read More
9
Magnesium therapy aids back pain
A double-blinded randomised controlled study of the value of sequential intravenous and oral magnesium therapy in patients with chronic low back pain with a neuropathic component.
We conducted a double-blind study to evaluate the effectiveness of magnesium therapy for chronic low back pain that has a neuropathic component. Our research involved 80 patients, all of whom were already engaged in physical therapy and taking medications like anticonvulsants and antidepressants.
Among the participants, we divided them into two groups: one group received a placebo for six weeks, while the other group was treated with a two-week intravenous magnesium infusion followed by four weeks of oral magnesium supplements.
The results were promising for those in the magnesium group. By the end of the study, their pain intensity decreased significantly, with scores dropping from an average of 7.5 to 4.7 over six months. Additionally, we observed notable improvements in their lumbar spine mobility, suggesting that magnesium therapy could be beneficial for those suffering from this type of chronic pain.
Overall, our findings indicate that sequential intravenous and oral magnesium treatment can effectively ease pain and enhance mobility in individuals with refractory low back pain featuring a neuropathic aspect.
I usually don’t write reviews, but I have to share. After two months of taking these vitamins, my back pain has ceased, and I wake up feeling refreshed. My cycle has normalised, and I’ve noticed significant hair growth. I highly recommend this for health!
Read More
10
Eliminated back pain
14 people found this helpful
I often suffered from back pain during my monthly cycle, but this raw calcium has completely alleviated it! I had previously experienced calcium deficiencies and chest pain from other supplements. Now, I hardly notice it’s that time of the month due to the absence of back pain.
Read More
9
Pain-free movement
7 people found this helpful
The best! After taking this for a couple of weeks, my osteoarthritis and osteoporosis pain disappeared. I was dancing again! When I ran out and couldn’t afford more, the pain returned until I found it cheaper on Amazon. This product works well when taken as recommended.
Read More
8
Significant back relief
6 people found this helpful
Having taken this for a couple of months, I felt great. After stopping, I noticed the old aches and pains return. I reordered, which was delivered the next day, and I can tell the difference; it makes my knees and back feel much better!
Read More
9
No more cramps
5 people found this helpful
This is the best calcium I’ve found! It contains D3 for absorption and K2 for directing calcium to bones and teeth. During my pregnancies, I suffered cramps with other calcium supplements, but this one has prevented all discomfort and pain. I recommend it to everyone, especially those pregnant or breastfeeding.
Back pain is a common ailment that affects millions of people worldwide and can vary significantly in intensity and duration. It can be classified into two main categories: acute and chronic. Acute back pain often arises suddenly due to a specific injury or strain, while chronic back pain persists for a longer duration, typically defined as lasting for 12 weeks or more. The pain can occur in various regions of the back, including the lower, middle, or upper sections, and may be accompanied by additional symptoms such as stiffness, muscle spasms, or reduced mobility.
Causes of back pain can range from poor posture, overexertion, or lifting heavy objects incorrectly to more serious conditions such as herniated discs, arthritis, or spinal abnormalities. Treatment options usually depend on the underlying cause and may include rest, physical therapy, medications, or, in some cases, surgical interventions. Maintaining a healthy lifestyle through regular exercise, proper ergonomics, and strength training can help prevent back pain and improve overall spinal health.
Calcium is a chemical element represented by the symbol Ca and atomic number 20. It is an essential mineral in the body, playing a critical role in various physiological processes. As one of the most abundant elements in nature, calcium is particularly vital for maintaining strong bones and teeth, where about 99% of the body's calcium is stored. Beyond its structural function, calcium is crucial in muscle contraction, blood clotting, and nerve transmission, making it a key player in overall health.
Dietary sources of calcium include dairy products such as milk, yogurt, and cheese, as well as leafy green vegetables, nuts, seeds, and fortified foods. The recommended daily intake of calcium varies by age and sex, but generally, adults should aim for approximately 1,000 mg per day. For those who may struggle to meet their needs through diet alone, calcium supplements are available but should be taken with caution. It's essential to consult with a healthcare provider before starting any supplement regimen to avoid potential side effects or interactions with medications.
Calcium plays an essential role in bone health, but its direct impact on back pain specifically is less clear. Back pain can stem from various issues, including muscle strain, herniated discs, or degenerative disc disease, and addressing these causes often requires a more comprehensive approach than just calcium supplementation. Adequate calcium intake contributes to strong bones, which can help prevent conditions like osteoporosis that may lead to back pain in older adults. However, taking additional calcium alone is unlikely to relieve back pain if the underlying cause is related to muscle or nerve issues.
For those experiencing back pain, it's often recommended to focus on a well-rounded diet that includes not only calcium but also other nutrients essential for muscle and bone health, such as vitamin D, magnesium, and protein. Additionally, engaging in physical therapy, regular exercise, and maintaining healthy body weight can be more effective strategies for managing and alleviating back pain. If you're considering calcium supplements or have concerns about your calcium intake, consulting with a healthcare provider is a good first step to tailor an approach that addresses your specific needs.
Based on user reviews, many individuals report relief from back pain within a week to two months of starting the supplement. For instance, one review noted significant improvement in back pain after just a week of use Read Review. Another user shared that their back pain ceased after two months of consistent intake Read Review.
Overall, while experiences may vary, the general consensus indicates that some users begin to feel noticeable effects on their back pain in the first week, with more substantial relief typically evident after a month or more. Consistency in taking the supplement appears to be a key factor in achieving these benefits, as suggested by the varying timelines reported by users.
When it comes to the use of calcium and vitamin D supplements for alleviating back pain, the scientific evidence presents a mixed picture. A study focused on a 70-year-old woman with osteoporosis showed significant improvement in her back pain after a year of combined calcium and vitamin D supplementation along with specific exercise. This suggests potential benefits of such supplementation on back pain and bone health [1]. However, further studies are noted to be necessary to isolate calcium's specific effects for more definitive conclusions.
In contrast, a systematic review of randomized controlled trials evaluating vitamin D supplementation in patients with chronic low back pain found no significant pain relief compared to control groups, regardless of participants' initial vitamin D levels [2]. Some cases indicated potential benefits of vitamin D treatment, particularly when combined with other therapies or targeted nutritional support. For instance, one study highlighted the relief of back pain in patients with low vitamin D who were treated alongside other medications [3]. Overall, while some research points to the possible advantages of calcium and vitamin D in managing back pain, particularly in conjunction with other treatment methods, further investigation is essential to accurately quantify their efficacy as standalone supplements.
Based on user reviews, many individuals have reported significant improvements in their symptoms after using the calcium supplement. Users highlighted various benefits, including the alleviation of back pain, normalization of menstrual cycles, and even noticeable hair growth. For example, one user noted their back pain ceased after two months of consistent use and also appreciated improvements in overall well-being Read Review. Another explicitly mentioned relief from back pain associated with their monthly cycle, emphasizing how this supplement has drastically changed their experience of that time Read Review.
Additional anecdotes indicate success with various types of pain, such as a reduction in knee and ankle discomfort after just a week or month of use Read Review, Read Review. Users have also noted improvements in joint health and mobility, with one user experiencing a decrease in finger joint swelling and back pain within days Read Review. While individual results can vary, the overwhelming consensus among users suggests that consistent use of the supplement can lead to substantial symptom relief.
Based on user reviews, many individuals have reported positive outcomes when combining this supplement with other dietary aids for back pain management. One user mentioned that taking this raw calcium in conjunction with a B-complex led to a noticeable reduction in morning pain associated with pre-existing hand issues Read Review. Another user noted that their experience with back pain significantly improved after they began using the supplement alongside glucosamine, particularly with relief from knee discomfort Read Review.
The integration of this calcium supplement with other health products appears to be well-received, as users report enhanced results in pain alleviation across various conditions. For example, one user saw substantial benefits in their muscle pain in addition to back pain after long-term use Read Review. Overall, combining this calcium supplement with other carefully selected vitamins or supplements seems to enhance user satisfaction and improve pain management results.
Users report a range of experiences regarding the effectiveness of calcium supplements in treating back pain, with many noting significant improvements after consistent use. For instance, one user mentioned that, after just a week of taking the supplement, their back pain had noticeably improved Read Review. Another user highlighted that their back pain ceased altogether after two months of use Read Review, suggesting that dosage and duration of intake could be important factors in achieving relief.
Several reviewers indicated that they took these supplements on medical advice and experienced marked improvements in their back pain issues. For example, a user noted that their back pain decreased significantly within a month of use Read Review. Additionally, one user affirmed that continuing with the calcium supplements helped alleviate their pain, and they would maintain their regimen moving forward Read Review. Such testimonials underscore the importance of consistency in taking calcium supplements, as users perceive variations in results depending on how long they maintained their dosage.
7.5
Bone pain improvement
The product's quality is exceptional. I felt improvement in my back pain after about a week of use. It’s a nutritional supplement packed with pure calcium. The only downside is the price relative to the quantity of pills, otherwise I’d repurchase.
9
Improved back pain
20 people found this helpful
I usually don’t write reviews, but I have to share. After two months of taking these vitamins, my back pain has ceased, and I wake up feeling refreshed. My cycle has normalised, and I’ve noticed significant hair growth. I highly recommend this for health!
10
Eliminated back pain
14 people found this helpful
I often suffered from back pain during my monthly cycle, but this raw calcium has completely alleviated it! I had previously experienced calcium deficiencies and chest pain from other supplements. Now, I hardly notice it’s that time of the month due to the absence of back pain.
9
Improved ankle pain
2 people found this helpful
After taking it for a week, my ankle pain has improved tremendously. There’s no pain now, so I will continue this calcium supplement.
9
Bone pain relief
After using this supplement for a month, I felt a significant improvement. My back pain has lessened, and I no longer experience the intense discomfort I had before.
7.5
Back pain relief
1 people found this helpful
As I age, I often suffer from swollen finger joints and back pain. After a week of this supplement, I feel improved. The plant-based formula aids calcium absorption; I’ll continue taking it for healthy bones.
7.5
Reduced hand pain
6 people found this helpful
I suffer from trigger thumbs and hand pain. After taking this product with a B-complex, I've noticed a significant reduction in morning pain. I recommend this product to anyone experiencing similar hand issues.
7.5
Knee pain improvement
I purchased more because it was on sale. I'm taking it with glucosamine, and I'm delighted my knee pain is improving. I intend to keep using it.
7.5
Relieved muscle pain
2 people found this helpful
I have taken Garden of Life Vitamin Code Raw Calcium for two years, as recommended by my doctor. I noticed a significant improvement in muscle pain in my shoulders and legs, and I feel lighter in the mornings. I highly recommend this for bone and cardiovascular health.
9
Calcium aids in back pain relief
Regular sling core stabilization training improves bone density based on calcium and vitamin D supplementation.
We explored the impact of calcium and vitamin D supplementation combined with sling core stabilization training on back pain in a 70-year-old female patient suffering from osteoporosis. The patient engaged in this form of exercise three times a week, focusing on strengthening the deep muscles of her spine.
After a year of dedicated training, not only did her back pain significantly improve, but a follow-up examination also indicated an increase in her bone mineral density. This suggests that the combined approach of exercise and supplementation might promote better bone health and potentially reduce pain.
However, it’s important to note that while we saw positive changes in this case, the specific contributions of calcium alone cannot be clearly identified due to the concurrent treatments involved. Therefore, we recognize that further studies are needed to isolate calcium's effects to conclusively determine its role in managing back pain effectively.
2
Vitamin D ineffective for back pain
Updated Meta-analysis Reveals Limited Efficacy of Vitamin D Supplementation in Chronic Low Back Pain.
We examined the effectiveness of vitamin D supplementation for people dealing with chronic low back pain (CLBP). Through a systematic review of randomized controlled trials, we focused on understanding whether vitamin D could bring any relief to those suffering from this persistent discomfort.
Our analysis of ten trials found that vitamin D supplementation did not lead to significant reductions in pain levels compared to control groups. This held true regardless of participants' initial vitamin D levels, and even long-term use did not show considerable improvements in pain outcomes. Interestingly, using active forms of vitamin D also failed to provide the hoped-for relief.
Despite these findings, it’s important to note that vitamin D might still play a role in a broader treatment plan for CLBP. However, as of now, there isn’t enough evidence to suggest that it can independently alleviate the pain. Further investigation is necessary to understand the potential long-term effects and the reasons behind the lack of benefit observed in our study.
9.5
Vitamin D aids back pain recovery
An Unusual Mimic of Axial Spondyloarthritis: A Case Report.
We observed a fascinating case involving a male in his 40s who experienced persistent inflammatory back pain for three months. Despite having a negative test for HLA-B27, a marker often associated with axial spondyloarthritis, clinical assessments suggested possible underlying issues.
The clinical investigation led to an MRI, which confirmed bilateral symmetrical sacroiliitis. Interestingly, further tests showed he had very low vitamin D levels along with elevated parathyroid hormone—indicating a possible deficiency impacting his condition.
After starting treatment with vitamin D alongside nonsteroidal anti-inflammatory drugs (NSAIDs), he experienced notable relief from his symptoms. His condition improved significantly, and follow-up tests indicated that his vitamin D levels had normalized.
This case demonstrates the potential benefits of vitamin D in managing back pain, especially when classical markers are inconclusive. It highlights how a thorough diagnosis can reveal interconnected health issues and improve treatment outcomes.
References
Liu J, Xu D, Liu L, Huang C, Guo Z, et al. Regular sling core stabilization training improves bone density based on calcium and vitamin D supplementation. BMC Musculoskelet Disord. 2023;24:815. doi:10.1186/s12891-023-06896-8
Lee TJ, Tsai RY, Ho CC, Chen CM, Li CP. Updated Meta-analysis Reveals Limited Efficacy of Vitamin D Supplementation in Chronic Low Back Pain. In Vivo. 2024;38:2955. doi:10.21873/invivo.13778
Bose S, Mohanasundaram K, Rajalakshmi KV, Perumal Kumaresan A, Simon J. An Unusual Mimic of Axial Spondyloarthritis: A Case Report. Cureus. 2024;16:e61441. doi:10.7759/cureus.61441
V N, Nair GG, Jose BC, Abraham A. Study on Vitamin D Levels in 30 to 40-Year-Old Females With Low Back Pain. Cureus. 2024;16:e54238. doi:10.7759/cureus.54238
Scaturro D, Vitagliani F, Tomasello S, Sconza C, Respizzi S, et al. Combined Rehabilitation with Alpha Lipoic Acid, Acetyl-L-Carnitine, Resveratrol, and Cholecalciferolin Discogenic Sciatica in Young People: A Randomized Clinical Trial. Medicina (Kaunas). 2023;59. doi:10.3390/medicina59122197
Kim S, Kim SW, Lee BC, Kim DH, Sung DH. Adult-onset hypophosphatemic osteomalacia as a cause of widespread musculoskeletal pain: A retrospective case series of single center experience. World J Clin Cases. 2023;11:7785. doi:10.12998/wjcc.v11.i32.7785
Ko S, Kim HC, Kwon J. The effectiveness of vitamin D3 supplementation in improving functional outcome of non-surgically treated symptomatic lumbar spinal stenosis: Randomized controlled clinical trial - Pilot study. Medicine (Baltimore). 2023;102:e32672. doi:10.1097/MD.0000000000032672
Evangelatos G, Kouna K, Iliopoulos A, Fragoulis GE. Musculoskeletal Complications of Celiac Disease: A Case-Based Review. Mediterr J Rheumatol. 2023;34:86. doi:10.31138/mjr.34.1.86
Dechsupa S, Yingsakmongkol W, Limthongkul W, Singhatanadgige W, Jitjumnong M, et al. Vitamin D Inadequacy Affects Skeletal Muscle Index and Physical Performance in Lumbar Disc Degeneration. Int J Mol Sci. 2023;24. doi:10.3390/ijms24043152
Dadkhah P, Hashemi M, Taheri M, Alizadeh Ojoor A, Jaffari M, et al. A Comparison of Analgesic Efficacy of Triamcinolone vs Magnesium Sulfate as Adjuvants in Caudal Block in Patients with Low Back Pain: A Double-Blind Randomized Controlled Trial. Anesth Pain Med. 2024;14:e145718. doi:10.5812/aapm-145718
Zhang T, Wang Y, Li R, Xin J, Zheng Z, et al. ROS-responsive magnesium-containing microspheres for antioxidative treatment of intervertebral disc degeneration. Acta Biomater. 2023;158:475. doi:10.1016/j.actbio.2023.01.020
Celenlioglu AE, Sir E, Ors-Yildirim N, Yildirim AK, Ince ME, et al. Effect of perioperative intravenous magnesium sulfate on postoperative pain after iliac venous stenting. J Vasc Surg Venous Lymphat Disord. 2023;11:517. doi:10.1016/j.jvsv.2022.09.008
Marchesi N, Govoni S, Allegri M. Non-drug pain relievers active on non-opioid pain mechanisms. Pain Pract. 2022;22:255. doi:10.1111/papr.13073
Huber D, Grafetstätter C, Proßegger J, Pichler C, Wöll E, et al. Green exercise and mg-ca-SO thermal balneotherapy for the treatment of non-specific chronic low back pain: a randomized controlled clinical trial. BMC Musculoskelet Disord. 2019;20:221. doi:10.1186/s12891-019-2582-4
Yousef AA, Al-deeb AE. A double-blinded randomised controlled study of the value of sequential intravenous and oral magnesium therapy in patients with chronic low back pain with a neuropathic component. Anaesthesia. 2013;68:260. doi:10.1111/anae.12107
Vormann J, Worlitschek M, Goedecke T, Silver B. Supplementation with alkaline minerals reduces symptoms in patients with chronic low back pain. J Trace Elem Med Biol. 2001;15:179.