Medical Researches
Possibly Effective
Based on 15 Researches
We observed a fascinating case involving a male in his 40s who experienced persistent inflammatory back pain for three months. Despite having a negative test for HLA-B27, a marker often associated with axial spondyloarthritis, clinical assessments suggested possible underlying issues.
The clinical investigation led to an MRI, which confirmed bilateral symmetrical sacroiliitis. Interestingly, further tests showed he had very low vitamin D levels along with elevated parathyroid hormone—indicating a possible deficiency impacting his condition.
After starting treatment with vitamin D alongside nonsteroidal anti-inflammatory drugs (NSAIDs), he experienced notable relief from his symptoms. His condition improved significantly, and follow-up tests indicated that his vitamin D levels had normalized.
This case demonstrates the potential benefits of vitamin D in managing back pain, especially when classical markers are inconclusive. It highlights how a thorough diagnosis can reveal interconnected health issues and improve treatment outcomes.
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We explored the effectiveness of magnesium sulfate (MS) in relieving low back pain (LBP) for patients who underwent iliac venous stenting. This study involved 97 patients, divided into two groups: one received MS infusion during their surgery, while the other did not.
Patients who received MS experienced significantly lower pain levels at all follow-up intervals. We found that, at 24 hours after surgery, those in the magnesium group consumed much less tramadol—a common pain medication—compared to the control group. Additionally, the need for extra pain relief was lower among those who received magnesium.
Importantly, the side effects like nausea and vomiting were similar in both groups, indicating that magnesium can be a safe option for pain management after this type of surgery. Overall, the findings suggest that magnesium sulfate not only alleviates pain but also reduces reliance on opioids, making it a valuable treatment for postoperative care.
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Vitamin D aids back pain reliefAdult-onset hypophosphatemic osteomalacia as a cause of widespread musculoskeletal pain: A retrospective case series of single center experience.
Significant relevance to treatment
We conducted a retrospective review to uncover how vitamin D treatment impacts back pain in individuals diagnosed with adult-onset hypophosphatemic osteomalacia. In our exploration, we found that eight patients, primarily experiencing widespread musculoskeletal pain, were assessed over a span from January 2011 to December 2019.
Each patient presented with low phosphorus levels, elevated alkaline phosphatase, and indicative imaging results. Notably, back pain was reported as the most common complaint, along with muscle weakness in over half of the cases. Our findings highlighted the effectiveness of vitamin D in tandem with phosphorus supplementation, as all patients reported significant improvements in pain, muscle strength, and gait after receiving treatment.
Importantly, we noted that the specific diagnosis of each patient varied. In six cases, treatment was prompted by adefovir-induced Fanconi syndrome, while the remaining two patients had tumor-induced osteomalacia and light-chain nephropathy. This variation indicates the diverse etiologies of hypophosphatemic osteomalacia, further emphasizing the importance of targeted treatment based on individual needs.
In conclusion, our study suggests that vitamin D, especially when combined with phosphorus, plays a crucial role in alleviating back pain associated with this condition. By enhancing the understanding of the relationship between vitamin D treatment and back pain, we aim to shed light on effective management strategies for those suffering from similar symptoms.
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Calcium aids in back pain reliefRegular sling core stabilization training improves bone density based on calcium and vitamin D supplementation.
Calcium's effects unclear in isolation
We explored the impact of calcium and vitamin D supplementation combined with sling core stabilization training on back pain in a 70-year-old female patient suffering from osteoporosis. The patient engaged in this form of exercise three times a week, focusing on strengthening the deep muscles of her spine.
After a year of dedicated training, not only did her back pain significantly improve, but a follow-up examination also indicated an increase in her bone mineral density. This suggests that the combined approach of exercise and supplementation might promote better bone health and potentially reduce pain.
However, it’s important to note that while we saw positive changes in this case, the specific contributions of calcium alone cannot be clearly identified due to the concurrent treatments involved. Therefore, we recognize that further studies are needed to isolate calcium's effects to conclusively determine its role in managing back pain effectively.
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Magnesium therapy aids back painA double-blinded randomised controlled study of the value of sequential intravenous and oral magnesium therapy in patients with chronic low back pain with a neuropathic component.
Explores magnesium's combined benefits
We conducted a double-blind study to evaluate the effectiveness of magnesium therapy for chronic low back pain that has a neuropathic component. Our research involved 80 patients, all of whom were already engaged in physical therapy and taking medications like anticonvulsants and antidepressants.
Among the participants, we divided them into two groups: one group received a placebo for six weeks, while the other group was treated with a two-week intravenous magnesium infusion followed by four weeks of oral magnesium supplements.
The results were promising for those in the magnesium group. By the end of the study, their pain intensity decreased significantly, with scores dropping from an average of 7.5 to 4.7 over six months. Additionally, we observed notable improvements in their lumbar spine mobility, suggesting that magnesium therapy could be beneficial for those suffering from this type of chronic pain.
Overall, our findings indicate that sequential intravenous and oral magnesium treatment can effectively ease pain and enhance mobility in individuals with refractory low back pain featuring a neuropathic aspect.
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